site stats

Thioredoxin domain-containing protein 2

WebThioredoxin is a 12-kD oxidoreductase protein. Thioredoxin proteins also have a characteristic ... the other conserved Cys residue in Trx1, forms a disulfide bond with Cys32, thereby transferring 2 electrons to the substrate which is now in its reduced form. ... the proteomics study found that SET and MYND domain-containing protein 1 (SMYD1), a ... WebThe thioredoxin (TXN) system and TXN-domain-containing protein (TXNDC) family form networks maintaining the cellular reducing environment. Recently, the importance of …

Thioredoxin - an overview ScienceDirect Topics

WebDec 1, 2024 · Besides TXNDC5, a total of more than 20 PDI family members have been identified in human cells. 5 As a common structural feature, all members of the PDI family contain one or more of the thioredoxin-like domain that consists of the signature sequence cysteine-X-X-cysteine (CXXC). The existence of multiple PDI members in mammalian cells … WebJul 8, 2024 · Interestingly, although several thioredoxin domain-containing proteins were present in the oxidoreductase enzyme cluster, two primary members of this class, thioredoxin reductase 1 and 2 were ... tmh day care center https://joesprivatecoach.com

Clinical Significance of the Thioredoxin System and Thioredoxin …

WebBy examining genes arising from intra- and interchromosomal duplications involving the ancestral chromosome 2 fusion site, followed by PCR of a fetal brain cDNA library, Fan et al. (2002) cloned CBWD2. They also identified the paralogs CBWD1 and CBWD3 ().No 2 of the 3 CBWD paralogs are identical, but they all encode a deduced 395-amino acid protein … WebThioredoxin domain-containing protein 2 is a protein that in humans is encoded by the TXNDC2 gene. References Further reading. This page was last edited on 4 March 2024, at 11:22 (UTC). Text is available under the Creative Commons Attribution-ShareAlike License 3.0; additional terms may ... Thioredoxins are small disulfide-containing redox proteins that have been found in all the kingdoms of living organisms. Thioredoxin serves as a general protein disulfide oxidoreductase. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulfide and a dithiol. tmh electrical

The role and mechanism of TXNDC5 in diseases European …

Category:Proteomics and gene expression analyses of squalene …

Tags:Thioredoxin domain-containing protein 2

Thioredoxin domain-containing protein 2

UniProt

WebMay 6, 2024 · We identified thioredoxin-binding protein-2 (TBP-2) as a protein that interacts with thioredoxin, which is an important regulator of the cellular oxidation/reduction (redox) system ... Arrestin domain-containing protein 3 recruits the NEDD4 E3 ligase to mediate ubiquitination of the beta2-adrenergic receptor. EMBO Rep 11: ... WebJan 18, 2024 · T hiosulfate Sulfurtransferase like Domain Containing 1 Protein Interacts with Thioredoxin Marouane Libiad 1 ǂ , Nicole Motl 1 ǂ , David L. Akey 2 , Naoya Sakamoto 4 , Eric R. Fearon 3 , Janet L ...

Thioredoxin domain-containing protein 2

Did you know?

WebFeb 10, 2024 · Thioredoxin (Trx) proteins, a class of conserved, thermostable, acidic small proteins [] that are widely found in chloroplasts, yeast, animals, and plants [2,3,4], share the highly conserved active site core sequence Trp-Cys-Gly-Pro-Cys (WCXXC).Within this core sequence, two Cys residues confer unique biological properties to Trx proteins by … WebThioredoxin-interacting protein (TXNIP), also known as thioredoxin-binding protein 2 (TBP-2)/vitamin D3up-regulated protein 1 (VDUP1), is an α-arrestin that can bind to and inhibit thioredoxin (the antioxidant protein). ... NLRP3, Nucleotide binding and oligomerization domain-like receptor family pyrin domain-containing 3; ROS, Reactive oxygen ...

WebMar 21, 2024 · TXNDC2 (Thioredoxin Domain Containing 2) is a Protein Coding gene. Diseases associated with TXNDC2 include Chromosome 18P Deletion Syndrome and Immunodeficiency 15B.Gene Ontology (GO) annotations related to this gene include … GLUL (Glutamate-Ammonia Ligase) is a Protein Coding gene. Diseases … G6PD (Glucose-6-Phosphate Dehydrogenase) is a Protein Coding … DDIT3 (DNA Damage Inducible Transcript 3) is a Protein Coding gene. Diseases … CD74 (CD74 Molecule) is a Protein Coding gene. Diseases associated with CD74 … GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) is a Protein Coding … WebJun 4, 2024 · Thioredoxin domain-containing protein 5 which plays role in apoptotic process and shows oxireductase activity within MM/MGUS plasma cells also displayed a …

WebNX_Q86VQ3 - TXNDC2 - Thioredoxin domain-containing protein 2 - Structures. Probably plays a regulatory role in sperm development. May participate in regulation of fibrous … WebMar 8, 2024 · The thioredoxin (TRX)-like superfamily is a large, diverse group of proteins containing a TRX fold. Many members contain a classic TRX domain with a redox active …

WebThe NLRP3 inflammasome is a multiprotein complex,which consisted of the NLRP3 protein,apoptosisassociated speck-like protein containing a CARD (ASC)and precursor caspase-1.5Interestingly,the combination of these factors can result in the production of inflammation molecules,such as interleukin 1beta (IL-1β) and interleukin-18 (IL-18).4

WebApr 7, 2024 · The C-terminal region of RNF111 shares approximately 45% sequence homology with its related E3 RNF165, and this sequence homology is particularly strong (> 80%) within the core RING domain [27, 28] (Fig. 1d).We therefore performed Flag co-immunoprecipitation (co-IP) of HA-UBXN7 with Flag-RNF165-WT or the size equivalent C … tmh email security portalWebMar 29, 2024 · NM_001350735.2 → NP_001337664.1 thioredoxin domain-containing protein 15 isoform 2. Status: REVIEWED. Description Transcript Variant: This variant (2) … tmh emergency room numberWebProteomics and gene expression analyses of squalene-supplemented mice identify microsomal thioredoxin domain-containing protein 5 changes associated with hepatic steatosis Author links open overlay panel Adela Ramírez-Torres a , Sílvia Barceló-Batllori b , Roberto Martínez-Beamonte a e , María A. Navarro c e , Joaquín C. Surra a e ... tmh emergency physicians group billingWebAbstract. Thioredoxin (Trx) is an inflammation-inducible small oxidoreductase protein ubiquitously expressed in all organisms. Trx acts both intracellularly and extracellularly … tmh employee benefitsWebThioredoxin binding protein -2-like inducible membrane protein/ arrestin domain containing 3 regulates endocytosis of receptors such as the β(2)-adrenergic receptor. The α-arrestin … tmh emergency room thomasville roadWebNissom et al. (2006) reported that full-length TXNDC5, which they called HCC2, contains 432 amino acids. By RT-PCR and 5-prime and 3-prime RACE, they identified a splice variant of HCC2 that was differentially upregulated in poorly defined hepatocellular carcinomas. The deduced 363-amino acid isoform has a calculated molecular mass of 40.7 kD. tmh employee discountsWebApr 14, 2024 · The fusion activity of 2 µM of the cyanobacterial IM30 protein, which is well-known to trigger the fusion of membranes containing TM lipids 60,88,89,90, was measured as a positive control. tmh employee